ONIMAI: I'm Now Your Sister!
お兄ちゃんはおしまい！
Synopsis
Mahiro Oyama was just a normal erotic-game loving dude…until he woke up one morning as a woman! Turns out his mad-scientist little sister, Mihari, tried out one of her new experiments on him…with a disastrous outcome, as far as Mahiro’s concerned! But Mihari is as determined to study him as he is determined to go back to his shut-in, game-playing life, and one thing’s for sure…life is going to get a whole lot weirder from here on out! (Source: Kodansha USA)
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